Publications

61 entries « 1 of 2 »

2024

Mansi, Salma; Dummert, Sarah V; Topping, Geoffrey J; Hussain, Mian Zahid; Rickert, Carolin; Mueller, Kilian MA; Kratky, Tim; Elsner, Martin; Casini, Angela; Schilling, Franz; others,

Introducing Metal–Organic Frameworks to Melt Electrowriting: Multifunctional Scaffolds with Controlled Microarchitecture for Tissue Engineering Applications Journal Article

In: Advanced Functional Materials, vol. 34, no. 2, pp. 2304907, 2024.

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Chaumeil, Myriam M; Bankson, James A; Brindle, Kevin M; Epstein, Shdema; Gallagher, Ferdia A; Grashei, Martin; Guglielmetti, Caroline; Kaggie, Joshua D; Keshari, Kayvan R; Knecht, Stephan; others,

New Horizons in Hyperpolarized 13C MRI Journal Article

In: Molecular Imaging and Biology, pp. 1–11, 2024.

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Wodtke, Pascal; Grashei, Martin; Schilling, Franz

Quo Vadis Hyperpolarized 13C MRI? Journal Article

In: Zeitschrift für Medizinische Physik, 2024.

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Larson, Peder EZ; Bernard, Jenna ML; Bankson, James A; Bøgh, Nikolaj; Bok, Robert A; Chen, Albert P; Cunningham, Charles H; Gordon, Jeremy W; Hövener, Jan-Bernd; Laustsen, Christoffer; others,

Current methods for hyperpolarized [1-13C] pyruvate MRI human studies Journal Article

In: Magnetic Resonance in Medicine, 2024.

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Kaika, Athanasia; Topping, Geoffrey J; Nagel, Luca; Schilling, Franz

Filter-exchange spectroscopy is sensitive to gradual cell membrane degradation Journal Article

In: NMR in Biomedicine, pp. e5202, 2024.

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Schmidt, Andreas Benjamin; Chekmenev, Eduard; Maissin, Henri; Groß, Philipp R; Petersen, Stefan; Nagel, Luca; Schilling, Franz; Schwartz, Ilai; Reinheckel, Thomas; Hövener, Jan-Bernd; others,

Signal Amplification By Reversible Exchange and its Translation to Hyperpolarized Magnetic Resonance Imaging in Biomedicine Journal Article

In: Analysis & Sensing, pp. e202400039, 2024.

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2023

Kitzberger, Carolin; Spellerberg, Rebekka; Han, Yang; Schmohl, Kathrin A; Stauss, Christina; Zach, Christian; Kälin, Roland E; Multhoff, Gabriele; Eiber, Mathias; Schilling, Franz; others,

Mesenchymal Stem Cell-mediated Image-guided Sodium Iodide Symporter (NIS) Gene Therapy Improves Survival of Glioblastoma-bearing Mice Journal Article

In: Clinical Cancer Research, vol. 29, no. 5, pp. 930–942, 2023.

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Gierse, Martin; Nagel, Luca; Keim, Michael; Lucas, Sebastian; Speidel, Tobias; Lobmeyer, Tobias; Winter, Gordon; Josten, Felix; Karaali, Senay; Fellermann, Maximilian; others,

Parahydrogen-Polarized Fumarate for Preclinical in Vivo Metabolic Magnetic Resonance Imaging Journal Article

In: Journal of the American Chemical Society, vol. 145, no. 10, pp. 5960–5969, 2023.

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Skinner, Jason G; Topping, Geoffrey J; Nagel, Luca; Heid, Irina; Hundshammer, Christian; Grashei, Martin; Heijster, Frits HA; Braren, Rickmer; Schilling, Franz

Spectrally selective bSSFP using off-resonant RF excitations permits high spatiotemporal resolution 3D metabolic imaging of hyperpolarized [1-13 C] Pyruvate-to-[1-13 C] lactate conversion. Journal Article

In: Magnetic Resonance in Medicine, 2023.

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Schillmaier, Mathias; Kaika, Athanasia; Topping, Geoffrey J; Braren, Rickmer; Schilling, Franz

Repeatability and reproducibility of apparent exchange rate measurements in yeast cell phantoms using filter-exchange imaging Journal Article

In: Magnetic Resonance in Medicine, vol. 90, no. 3, pp. 894–909, 2023.

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Maissin, Henri; Groß, Philipp; Mohiuddin, Obaid; Weigt, Moritz; Nagel, Luca; Herzog, Marvin; Wang, Zirun; Willing, Robert; Reichardt, Wilfried; Pichotka, Martin; others,

In Vivo Metabolic Imaging of [1-13C] Pyruvate-d3 Hyperpolarized By Reversible Exchange With Parahydrogen Journal Article

In: Angewandte Chemie, vol. 62, no. 36, pp. e202306654, 2023.

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Nagel, Luca; Gierse, Martin; Gottwald, Wolfgang; Ahmadova, Zumrud; Grashei, Martin; Wolff, Pascal; Josten, Felix; Karaali, Senay; Müller, Christoph A; Lucas, Sebastian; others,

Parahydrogen-Polarized [1-13C] Pyruvate For Reliable and Fast Preclinical Metabolic Magnetic Resonance Imaging Journal Article

In: Advanced Science, vol. 10, no. 30, pp. 2303441, 2023.

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Deline, Marshall Lee; Straub, Joshua; Patel, Manisha; Subba, Pratigya; Grashei, Martin; Heijster, Frits; Pirkwieser, Philip; Somoza, Veronika; Livingstone, James D; Beazely, Michael A; others,

Lithium isotopes differentially modify mitochondrial amorphous calcium phosphate cluster size distribution and calcium capacity Journal Article

In: Frontiers in Physiology, vol. 14, pp. 1200119, 2023.

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Kitzberger, Carolin; Shehzad, Khuram; Morath, Volker; Spellerberg, Rebekka; Ranke, Julius; Steiger, Katja; Kälin, Roland E; Multhoff, Gabriele; Eiber, Matthias; Schilling, Franz; others,

Interleukin-6-Controlled, Mesenchymal Stem Cell-based Sodium/Iodide Symporter Gene Therapy Improves Survival of Glioblastoma-bearing Mice Journal Article

In: Molecular Therapy-Oncolytics, vol. 30, pp. 238–253, 2023.

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Grashei, Martin; Wodtke, Pascal; Skinner, Jason G; Sühnel, Sandra; Setzer, Nadine; Metzler, Thomas; Gulde, Sebastian; Park, Mihyun; Witt, Daniela; Mohr, Hermine; others,

Simultaneous magnetic resonance imaging of pH, perfusion and renal filtration using hyperpolarized 13C-labelled Z-OMPD Journal Article

In: Nature Communications, vol. 14, no. 1, pp. 5060, 2023.

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Wartewig, Tim; Daniels, Jay; Schulz, Miriam; Hameister, Erik; Joshi, Abhinav; Park, Joonhee; Morrish, Emma; Venkatasubramani, Anuroop V; Cernilogar, Filippo M; Heijster, Frits HA; others,

PD-1 instructs a tumor-suppressive metabolic program that restricts glycolysis and restrains AP-1 activity in T cell lymphoma Journal Article

In: Nature Cancer, vol. 4, no. 10, pp. 1508–1525, 2023.

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2022

Liu, Zhen; Cheng, Tao; Düwel, Stephan; Jian, Ziying; Topping, Geoffrey J; Steiger, Katja; Wang, Qian; Braren, Rickmer; Reder, Sybille; Mittelhäuser, Markus; others,

Proof of concept of a multimodal intravital molecular imaging system for tumour transpathology investigation Journal Article

In: European journal of nuclear medicine and molecular imaging, vol. 49, no. 4, pp. 1157–1165, 2022.

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Karabid, Ninelia Minaskan; Wiedemann, Tobias; Gulde, Sebastian; Mohr, Hermine; Segaran, Renu Chandra; Geppert, Julia; Rohm, Maria; Vitale, Giovanni; Gaudenzi, Germano; Dicitore, Alessandra; others,

Angpt2/Tie2 autostimulatory loop controls tumorigenesis Journal Article

In: EMBO Molecular Medicine, vol. 14, no. 5, pp. e14364, 2022.

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Grashei, Martin; Biechl, Philipp; Schilling, Franz; Otto, Angela M

Conversion of Hyperpolarized [1-13C] Pyruvate in Breast Cancer Cells Depends on Their Malignancy, Metabolic Program and Nutrient Microenvironment Journal Article

In: Cancers, vol. 14, no. 7, pp. 1845, 2022.

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Fok, Wai-Yan Ryana; Grashei, Martin; Skinner, Jason G; Menze, Bjoern H; Schilling, Franz

Prediction of multiple pH compartments by deep learning in magnetic resonance spectroscopy with hyperpolarized 13C-labelled zymonic acid Journal Article

In: EJNMMI research, vol. 12, no. 1, pp. 1–14, 2022.

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Kitzberger, Carolin; Spellerberg, Rebekka; Morath, Volker; Schwenk, Nathalie; Schmohl, Kathrin A; Schug, Christina; Urnauer, Sarah; Tutter, Mariella; Eiber, Matthias; Schilling, Franz; others,

The sodium iodide symporter (NIS) as theranostic gene: its emerging role in new imaging modalities and non-viral gene therapy Journal Article

In: EJNMMI research, vol. 12, no. 1, pp. 1–14, 2022.

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Spellerberg, Rebekka; Benli-Hoppe, Teoman; Kitzberger, Carolin; Hageneier, Mara; Schwenk, Nathalie; Öztürk, Özgür; Steiger, Katja; Multhoff, Gabriele; Eiber, Matthias; Schilling, Franz; others,

Dual EGFR-and TfR-targeted Gene Transfer Improves Efficacy of Sodium Iodide Symporter (NIS) Gene Therapy of Glioblastoma Journal Article

In: Molecular Therapy-Oncolytics, 2022.

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Heid, Irina; Münch, Corinna; Karakaya, Sinan; Lueong, Smiths S; Winkelkotte, Alina M; Liffers, Sven T; Godfrey, Laura; Cheung, Phyllis FY; Savvatakis, Konstantinos; Topping, Geoffrey J; others,

Functional noninvasive detection of glycolytic pancreatic ductal adenocarcinoma Journal Article

In: Cancer & Metabolism, vol. 10, no. 1, pp. 1–14, 2022.

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2021

Bliemsrieder, Elisabeth; Kaissis, Georgios; Grashei, Martin; Topping, Geoffrey; Altomonte, Jennifer; Hundshammer, Christian; Lohöfer, Fabian; Heid, Irina; Keim, Dominik; Gebrekidan, Selamawit; others,

Hyperpolarized 13 C pyruvate magnetic resonance spectroscopy for in vivo metabolic phenotyping of rat HCC Journal Article

In: Scientific reports, vol. 11, no. 1, pp. 1–9, 2021.

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Topping, Geoffrey J; Heid, Irina; Trajkovic-Arsic, Marija; Kritzner, Lukas; Grashei, Martin; Hundshammer, Christian; Aigner, Maximilian; Skinner, Jason G; Braren, Rickmer; Schilling, Franz

Hyperpolarized 13C Spectroscopy with Simple Slice-and-Frequency-Selective Excitation Journal Article

In: Biomedicines, vol. 9, no. 2, pp. 121, 2021.

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Deline, Marshall L; Grashei, Martin; Heijster, Frits HA; Schilling, Franz; Straub, Joshua; Fromme, Tobias

Adenylate kinase derived ATP shapes respiration and calcium storage of isolated mitochondria Journal Article

In: Biochimica et Biophysica Acta (BBA)-Bioenergetics, vol. 1862, no. 7, pp. 148409, 2021.

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Grashei, Martin; Hundshammer, Christian; Heijster, Frits HA; Topping, Geoffrey J; Schilling, Franz

pH Dependence of T2 for Hyperpolarizable 13C-Labelled Small Molecules Enables Spatially Resolved pH Measurement by Magnetic Resonance Imaging Journal Article

In: Pharmaceuticals, vol. 14, no. 4, pp. 327, 2021.

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Volmar, Marie NM; Cheng, Jiying; Alenezi, Haitham; Richter, Sven; Haug, Alisha; Hassan, Zonera; Goldberg, Maria; Li, Yuping; Hou, Mengzhuo; Herold-Mende, Christel; others,

Cannabidiol converts NF (κ) B into a tumor suppressor in glioblastoma with defined antioxidative properties Journal Article

In: Neuro-oncology, vol. 23, no. 11, pp. 1898–1910, 2021.

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Gulde, Sebastian; Wiedemann, Tobias; Schillmaier, Mathias; Valença, Isabel; Lupp, Amelie; Steiger, Katja; Yen, Hsi-Yu; Bäuerle, Stephen; Notni, Johannes; Luque, Raul; others,

Gender-Specific Efficacy Revealed by Head-to-Head Comparison of Pasireotide and Octreotide in a Representative In Vivo Model of Nonfunctioning Pituitary Tumors Journal Article

In: Cancers, vol. 13, no. 12, pp. 3097, 2021.

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Kilian, MA; Topping, GJ; Schwaminger, SP; Zou, Y; Roja-González, DM; Pardo, EM De-Juan; Berensmeier, S; Schilling, F; Mela, P

Visualization of USPIO-labeled melt-electrowritten scaffolds by non-invasive magnetic resonance imaging Journal Article

In: Biomaterials Science, vol. 9, no. 13, pp. 4607–4612, 2021.

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Spellerberg, Rebekka; Benli-Hoppe, Teoman; Kitzberger, Carolin; Berger, Simone; Schmohl, Kathrin A; Schwenk, Nathalie; Yen, Hsi-Yu; Zach, Christian; Schilling, Franz; Weber, Wolfgang A; others,

Selective sodium iodide symporter (NIS) genetherapy of glioblastoma mediatedby EGFR-targeted lipopolyplexes Journal Article

In: Molecular Therapy-Oncolytics, vol. 23, pp. 432–446, 2021.

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Mohr, Hermine; Foscarini, Alessia; Steiger, Katja; Ballke, Simone; Rischpler, Christoph; Schilling, Franz; Pellegata, Natalia S

Imaging pheochromocytoma in small animals: preclinical models to improve diagnosis and treatment Journal Article

In: EJNMMI research, vol. 11, no. 1, pp. 1–14, 2021.

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2020

Berninger, Markus T; Rodriguez-Gonzalez, Pablo; Schilling, Franz; Haller, Bernhard; Lichtenstein, Thorsten; Imhoff, Andreas B; Rummeny, Ernst J; Anton, Martina; Vogt, Stephan; Henning, Tobias D

Bifunctional Labeling of Rabbit Mesenchymal Stem Cells for MR Imaging and Fluorescence Microscopy Journal Article

In: Molecular Imaging and Biology, pp. 1–10, 2020.

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Topping, Geoffrey J; Hundshammer, Christian; Nagel, Luca; Grashei, Martin; Aigner, Maximilian; Skinner, Jason G; Schulte, Rolf F; Schilling, Franz

Acquisition strategies for spatially resolved magnetic resonance detection of hyperpolarized nuclei Journal Article

In: Magnetic Resonance Materials in Physics, Biology and Medicine, vol. 33, no. 2, pp. 221–256, 2020.

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Lohöfer, Fabian; Buchholz, Rebecca; Glinzer, Almut; Huber, Katharina; Haas, Helena; Kaissis, Georgios; Feuchtinger, Annette; Aichler, Michaela; Sporns, Peter B; Höltke, Carsten; others,

Mass spectrometry imaging of atherosclerosis-affine gadofluorine following magnetic resonance imaging Journal Article

In: Scientific reports, vol. 10, no. 1, pp. 1–9, 2020.

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Schillmaier, Mathias; Kaika, Athanasia; Schilling, Franz

Disentangling Intercompartment Exchange from Restricted Diffusion Journal Article

In: Advanced Diffusion Encoding Methods in MRI, vol. 24, pp. 154, 2020.

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Müller, Christoph A; Hundshammer, Christian; Braeuer, Miriam; Skinner, Jason G; Berner, Stephan; Leupold, Jochen; Düwel, Stephan; Nekolla, Stephan G; Månsson, Sven; Hansen, Adam E; others,

Dynamic 2D and 3D mapping of hyperpolarized pyruvate to lactate conversion in vivo with efficient multi-echo balanced steady-state free precession at 3 T Journal Article

In: NMR in Biomedicine, vol. 33, no. 6, pp. e4291, 2020.

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2019

Herzen, Julia; Karampinos, Dimitrios C; Foehr, Peter; Birnbacher, Lorenz; Viermetz, Manuel; Burgkart, Rainer; Baum, Thomas; Lohoefer, Fabian; Wildgruber, Moritz; Schilling, Franz; others,

3D grating-based X-ray phase-contrast computed tomography for high-resolution quantitative assessment of cartilage: An experimental feasibility study with 3T MRI, 7T MRI and biomechanical correlation Journal Article

In: PloS one, vol. 14, no. 2, pp. e0212106, 2019.

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Hundshammer, Christian; Grashei, Martin; Greiner, Alexandra; Glaser, Steffen J; Schilling, Franz

pH Dependence of T1 for 13C-Labelled Small Molecules Commonly Used for Hyperpolarized Magnetic Resonance Imaging Journal Article

In: ChemPhysChem, vol. 20, no. 6, pp. 798–802, 2019.

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2018

Hundshammer, Christian; Düwel, Stephan; Ruseckas, David; Topping, Geoffrey; Dzien, Piotr; Müller, Christoph; Feuerecker, Benedikt; Hövener, Jan B; Haase, Axel; Schwaiger, Markus; others,

Hyperpolarized amino acid derivatives as multivalent magnetic resonance pH sensor molecules Journal Article

In: Sensors, vol. 18, no. 2, pp. 600, 2018.

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Lohöfer, Fabian; Hoffmann, Laura; Buchholz, Rebecca; Huber, Katharina; Glinzer, Almut; Kosanke, Katja; Feuchtinger, Annette; Aichler, Michaela; Feuerecker, Benedikt; Kaissis, Georgios; others,

Molecular imaging of myocardial infarction with Gadofluorine P–A combined magnetic resonance and mass spectrometry imaging approach Journal Article

In: Heliyon, vol. 4, no. 4, pp. e00606, 2018.

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Hundshammer, Christian; Braeuer, Miriam; Müller, Christoph A; Hansen, Adam E; Schillmaier, Mathias; Düwel, Stephan; Feuerecker, Benedikt; Glaser, Steffen J; Haase, Axel; Weichert, Wilko; others,

Simultaneous characterization of tumor cellularity and the Warburg effect with PET, MRI and hyperpolarized 13C-MRSI Journal Article

In: Theranostics, vol. 8, no. 17, pp. 4765, 2018.

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Köcher, Simone S; Düwel, Stephan; Hundshammer, Christian; Glaser, Steffen J; Schilling, Franz; Granwehr, Josef; Scheurer, Christoph

Ab Initio Simulation of pH-Sensitive Biomarkers in Magnetic Resonance Imaging Journal Article

In: The Journal of Physical Chemistry A, vol. 122, no. 40, pp. 7983–7990, 2018.

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Cabello, J; Schilling, F; Nekolla, S

Technical and Methodological Aspects of Whole-body MR-PET Book Section

In: Hybrid MR-PET Imaging, pp. 300–316, 2018.

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2017

Schilling, Franz; Ros, Susana; Hu, De-En; D’Santos, Paula; McGuire, Sarah; Mair, Richard; Wright, Alan J; Mannion, Elizabeth; Franklin, Robin JM; Neves, André A; others,

MRI measurements of reporter-mediated increases in transmembrane water exchange enable detection of a gene reporter Journal Article

In: Nature biotechnology, vol. 35, no. 1, pp. 75–80, 2017.

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Düwel, Stephan; Hundshammer, Christian; Gersch, Malte; Feuerecker, Benedikt; Steiger, Katja; Buck, Achim; Walch, Axel; Haase, Axel; Glaser, Steffen J; Schwaiger, Markus; others,

Imaging of pH in vivo using hyperpolarized 13 C-labelled zymonic acid Journal Article

In: Nature communications, vol. 8, no. 1, pp. 1–9, 2017.

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Hundshammer, Christian; Düwel, Stephan; Schilling, Franz

Imaging of extracellular pH using hyperpolarized molecules Journal Article

In: Israel Journal of Chemistry, vol. 57, no. 9, pp. 788–799, 2017.

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Hundshammer, Christian; Düwel, Stephan; Köcher, Simone S; Gersch, Malte; Feuerecker, Benedikt; Scheurer, Christoph; Haase, Axel; Glaser, Steffen J; Schwaiger, Markus; Schilling, Franz

Deuteration of hyperpolarized 13C-labeled zymonic acid enables sensitivity-enhanced dynamic MRI of pH Journal Article

In: ChemPhysChem, vol. 18, no. 18, pp. 2422–2425, 2017.

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Feuerecker, Benedikt; Durst, Markus; Michalik, Michael; Schneider, Günter; Saur, Dieter; Menzel, Marion; Schwaiger, Markus; Schilling, Franz

Hyperpolarized 13C diffusion MRS of co-polarized Pyruvate and Fumarate to measure lactate export and necrosis Journal Article

In: Journal of Cancer, vol. 8, no. 15, pp. 3078, 2017.

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2016

Schilling, Franz; Glaser, Steffen; Düwel, Stephan; Gersch, Malte

pH-Biosensors Based on Compounds Produced From Pyruvic Acid For Magnetic Resonance Imaging and Spectroscopy and Their Uses Miscellaneous

2016, (US Patent App. 15/028,219).

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61 entries « 1 of 2 »